Substance P 2TFA Inhibitor

Substance P (1-7) 2TFA(68060-49-1(free base)) is the major bioactive metabolite formed after proteolytic degradation of the tachykinin substance P (SP),with anti-inflammatory, anti-nociceptive and anti-hyperalgesic effects

Herrera-Marschitz M, Terenius L, Sakurada T, et al. The substance P(1-7) fragment is a potent modulator of substance P actions in the brain[J]. Brain Research, 1990, 521(1-2):316-320.
Herrera-Marschitz M, Terenius L, Sakurada T, et al. The substance P(1-7) fragment is a potent modulator of substance P actions in the brain[J]. Brain Research, 1990, 521(1-2):316-320.
Skogh A, Lesniak A, Gaugaz F Z, et al. Impact of N -methylation of the substance P 1-7 amide on anti-allodynic effect in mice after peripheral administration[J]. European Journal of Pharmaceutical Sciences, 2017, 109.
Skogh A, Lesniak A, Gaugaz F Z, et al. Impact of N -methylation of the substance P 1-7 amide on anti-allodynic effect in mice after peripheral administration[J]. European Journal of Pharmaceutical Sciences, 2017, 109.

Small volumes of Substance P 2TFA, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5758566 is an inhibitor targeting Substance P 2TFA. Also known as Substance P (1-7) 2TFA (68060-49-1(free base)).