JNKVIII Inhibitor – JNK VIII

Name: JNKVIII Inhibitor; JNK VIII; MyBioSource
Brand: MyBioSource
SKU: MBS5758568
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5758568

JNK Inhibitor VIII is an ATP-competitive selective inhibitor of c-Jun N-terminal kinase (JNK)(IC50 values of 45nM and 160nM for JNK-1 and -2, respectively). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

JNK VIII (JNKVIII), Inhibitor

Full Product Name

JNK Inhibitor VIII

Product Gene Name

JNKVIII, inhibitor

Product Synonym Names

TCS JNK 6o

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

356.38

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C18H20N4O4

SMILES

CCOc1nc(NC(=O)Cc2cc(OC)ccc2OC)cc(N)c1C#N

CAS Number

894804-07-0

Target & IC50

JNK1: ic50 2nM (Ki)
JNK2: ic50 160nM
JNK3: ic50 52nM (Ki)

Product Categories/Family for JNKVIII, inhibitor

MAPK; JNK

Product References and Citations for JNKVIII, inhibitor

Szczepankiewicz BG, et al. Aminopyridine-based c-Jun N-terminal kinase inhibitors with cellular activity and minimal cross-kinase activity. J Med Chem. 2006 Jun 15;49(12):3563-80.

Other Notes

Small volumes of JNKVIII, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for JNKVIII purchase

MBS5758568 is an inhibitor targeting JNKVIII. Also known as JNK Inhibitor VIII.