3-Cyano-7-ethoxycoumarin Inhibitor

MBS5758586 is an inhibitor targeting 3-Cyano-7-ethoxycoumarin. 3-Cyano-7-ethoxycoumarin is cytochrome P450 (CYP) isoforms CYP1A1 and CYP1A2.

White I N H. A continuous fluorometric assay for cytochrome P-450-dependent mixed function oxidases using 3-cyano-7-ethoxycoumarin[J]. Analytical Biochemistry, 1988, 172(2):304-310.
White I N H. A continuous fluorometric assay for cytochrome P-450-dependent mixed function oxidases using 3-cyano-7-ethoxycoumarin[J]. Analytical Biochemistry, 1988, 172(2):304-310.
Dong A N, Ahemad N, Pan Y, et al. Functional and structural characterisation of common cytochrome P450 2D6 allelic variants-roles of Pro34 and Thr107 in catalysis and inhibition[J]. Naunyn-Schmiedeberg's Archives of Pharmacology, 2019.
Dong A N, Ahemad N, Pan Y, et al. Functional and structural characterisation of common cytochrome P450 2D6 allelic variants-roles of Pro34 and Thr107 in catalysis and inhibition[J]. Naunyn-Schmiedeberg's Archives of Pharmacology, 2019.

Small volumes of 3-Cyano-7-ethoxycoumarin, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.