AZD-7325 Inhibitor

MBS5758589 is an inhibitor targeting AZD-7325. AZD-7325 is a GABA-Aalpha2,3 -selective receptor modulator.

ProfileToshihiro Nomura, et al. Potentiating alpha2 subunit containing perisomatic GABAA receptors protects against seizures in a mouse model of Dravet Syndrome
ProfileToshihiro Nomura, et al. Potentiating alpha2 subunit containing perisomatic GABAA receptors protects against seizures in a mouse model of Dravet Syndrome
Chen X, et al. The central nervous system effects of the partial GABA-Aalpha2,3 -selective receptor modulator AZD7325 in comparison with lorazepam in healthy males. Br J Clin Pharmacol. 2014 Dec;78(6):1298-314.
Chen X, et al. The central nervous system effects of the partial GABA-Aalpha2,3 -selective receptor modulator AZD7325 in comparison with lorazepam in healthy males. Br J Clin Pharmacol. 2014 Dec;78(6):1298-314.

Small volumes of AZD-7325, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.