Lersivirine Inhibitor

Name: Lersivirine Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5758590
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5758590

Lersivirine(UK 453061) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) under development for HIV infection therapy. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Lersivirine, Inhibitor

Full Product Name

Lersivirine(UK 453061)

Product Synonym Names

Lersivirine; UK-453061

Form/Format

Solid. Powder

Purity/Purification

99.26%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

310.35

Solubility

DMSO: 50mg/mL (161.11mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C17H18N4O2

SMILES

CCc1nn(CCO)c(CC)c1Oc1cc(C#N)cc(C#N)c1

CAS Number

473921-12-9

Target & IC50

HIV

Product Categories/Family for Lersivirine, inhibitor

Microbiology/Virology; HIV Protease

Product References and Citations for Lersivirine, inhibitor

Davis J, et al. The effect of lersivirine, a next-generation NNRTI, on the pharmacokinetics of midazolam and oral contraceptives in healthy subjects. Eur J Clin Pharmacol. 2012 Nov;68(11):1567-72.
Davis J, et al. The effect of lersivirine, a next-generation NNRTI, on the pharmacokinetics of midazolam and oral contraceptives in healthy subjects. Eur J Clin Pharmacol. 2012 Nov;68(11):1567-72.
Mowbray CE, et al. Pyrazole NNRTIs 4: selection of UK-453,061 (lersivirine) as a development candidate. Bioorg Med Chem Lett. 2009 Oct 15;19(20):5857-60.
Mowbray CE, et al. Pyrazole NNRTIs 4: selection of UK-453,061 (lersivirine) as a development candidate. Bioorg Med Chem Lett. 2009 Oct 15;19(20):5857-60.

Other Notes

Small volumes of Lersivirine, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Lersivirine purchase

MBS5758590 is an inhibitor targeting Lersivirine. Also known as Lersivirine(UK 453061).