• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

GW405833 Inhibitor – Gw 405833

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5758593

MBS5758593 is an inhibitor targeting GW405833. Also known as GW 405833. GW 405833 is an agonist of cannabinoid-2 (CB(2)) receptor-selective More details

Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GW 405833 (GW405833), Inhibitor
Full Product Name
GW 405833
Product Gene Name
Product Synonym Names
L-768242
Form/Format
Solid. Powder
Purity/Purification
99.82%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
447.35
Solubility
DMSO: 10 mg/mL (22.35mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C23H24Cl2N2O3
SMILES
COc1ccc2c(c1)c(CCN1CCOCC1)c(C)n2C(=O)c1cccc(Cl)c1Cl
CAS Number
180002-83-9
Target & IC50
CB2

Structure of GW405833, inhibitor

GW405833 Inhibitor – Cat# MBS5758593

Product References and Citations for GW405833, inhibitor

Li A L, Carey L M, Mackie K, et al. The cannabinoid CB 2 agonist GW405833 suppresses inflammatory and neuropathic pain through a CB 1 mechanism that is independent of CB 2 receptors in mice[J]. Journal of Pharmacology and Experimental Therapeutics, 2017, 362(2):jpet.117.241901.
Li A L, Carey L M, Mackie K, et al. The cannabinoid CB 2 agonist GW405833 suppresses inflammatory and neuropathic pain through a CB 1 mechanism that is independent of CB 2 receptors in mice[J]. Journal of Pharmacology and Experimental Therapeutics, 2017, 362(2):jpet.117.241901.
Parlar A, Arslan S, Dogan, Muhammed, et al. The exogenous administration of CB2 specific agonist, GW405833, inhibits inflammation by reducing cytokine production and oxidative stress[J]. Experimental and Therapeutic Medicine, 2018.
Parlar A, Arslan S, Dogan, Muhammed, et al. The exogenous administration of CB2 specific agonist, GW405833, inhibits inflammation by reducing cytokine production and oxidative stress[J]. Experimental and Therapeutic Medicine, 2018.
Huang Z, Wang H, Wang J, et al. Cannabinoid receptor subtype 2 (CB2R) agonist, GW405833 reduces agonist-induced Ca2+ oscillations in mouse pancreatic acinar cells[J]. Scientific Reports, 2016, 6(1):29757.
Huang Z, Wang H, Wang J, et al. Cannabinoid receptor subtype 2 (CB2R) agonist, GW405833 reduces agonist-induced Ca2+ oscillations in mouse pancreatic acinar cells[J]. Scientific Reports, 2016, 6(1):29757.

Other Notes

Small volumes of GW405833, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000