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Ganaxolone Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5758607

Ganaxolone is a positive allosteric modulator of the action of the GABAA receptor, acts on well-characterized targets in the brain known to have anxiolytic and anticonvulsant effects. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Ganaxolone, Inhibitor
Full Product Name
Ganaxolone
Form/Format
Solid. Powder
Purity/Purification
99.94%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
332.52
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C22H36O2
SMILES
CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@](C)(O)CC[C@]4(C)[C@H]3CC[C@]12C
CAS Number
38398-32-2
Target & IC50
GABAA

Product References and Citations for Ganaxolone, inhibitor

Graziano P, Rasmusson A M. Ganaxolone improves behavioral deficits in a mouse model of post-traumatic stress disorder[J]. Frontiers in Cellular Neuroscience, 2014, 8.
Graziano P, Rasmusson A M. Ganaxolone improves behavioral deficits in a mouse model of post-traumatic stress disorder[J]. Frontiers in Cellular Neuroscience, 2014, 8.
Zolkowska D, Wu C Y, Rogawski M A. Intramuscular allopregnanolone and ganaxolone in a mouse model of treatment,resistant status epilepticus[J]. Epilepsia, 2018, 59 Suppl 2(Suppl. 5).
Zolkowska D, Wu C Y, Rogawski M A. Intramuscular allopregnanolone and ganaxolone in a mouse model of treatment,resistant status epilepticus[J]. Epilepsia, 2018, 59 Suppl 2(Suppl. 5).
Mares P, Mariana Stehlikova. Anticonvulsant doses of ganaxolone do not compromise motor performance in immature rats[J]. Neuroscience Letters, 2009, 469(3):396-399.
Mares P, Mariana Stehlikova. Anticonvulsant doses of ganaxolone do not compromise motor performance in immature rats[J]. Neuroscience Letters, 2009, 469(3):396-399.

Other Notes

Small volumes of Ganaxolone, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ganaxolone purchase

MBS5758607 is an inhibitor targeting Ganaxolone.
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