Losartan Carboxaldehyde Inhibitor

MBS5758701 is an inhibitor targeting Losartan Carboxaldehyde. Losartan Carboxaldehyde is an endothelial cyclooxygenase (COX)-2 inhibitor.

Kramer, C. Angiotensin II Receptor-Independent Antiinflammatory and Antiaggregatory Properties of Losartan: Role of the Active Metabolite EXP3179[J]. Circulation Research, 2002, 90(7):770-776.
Kramer, C. Angiotensin II Receptor-Independent Antiinflammatory and Antiaggregatory Properties of Losartan: Role of the Active Metabolite EXP3179[J]. Circulation Research, 2002, 90(7):770-776.
Schupp M, Lee L D, Frost N, et al. Regulation of Peroxisome Proliferator-Activated Receptor Activity by Losartan Metabolites[J]. Hypertension, 2006, 47(3):586-589.
Schupp M, Lee L D, Frost N, et al. Regulation of Peroxisome Proliferator-Activated Receptor Activity by Losartan Metabolites[J]. Hypertension, 2006, 47(3):586-589.

Small volumes of Losartan Carboxaldehyde, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.