SM324405 Inhibitor – Sm 324405

MBS5758723 is an inhibitor targeting SM324405. Also known as SM 324405. SM 324405 is an agonist of TLR7.

Kurimoto A, Hashimoto K, Nakamura T.Synthesis and biological evaluation of 8-oxoadenine derivatives as toll-like receptor 7 agonists introducing the antedrug concept[J].J Med Chem. 2010 Apr 8 ;53(7):2964-7
Kurimoto A, Hashimoto K, Nakamura T.Synthesis and biological evaluation of 8-oxoadenine derivatives as toll-like receptor 7 agonists introducing the antedrug concept[J].J Med Chem. 2010 Apr 8 ;53(7):2964-72.
Biological characterization of a novel class of toll-like receptor 7 agonists designed to have reduced systemic activity[J]. British Journal of Pharmacology, 2012, 166(2).
Biological characterization of a novel class of toll-like receptor 7 agonists designed to have reduced systemic activity[J]. British Journal of Pharmacology, 2012, 166(2).

Small volumes of SM324405, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.