BYK204165 Inhibitor

Name: BYK204165 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5758758
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5758758

BYK204165 is a potent PARP inhibitor (PARP1; IC50 = 44.67nM for human recombinant PARP1 in an enzyme assay) More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

BYK204165, Inhibitor

Full Product Name

BYK204165

Product Gene Name

BYK204165, inhibitor

Product Synonym Names

RT-017290

Form/Format

Solid. Powder

Purity/Purification

99.61%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

252.00

Solubility

DMSO: 125mg/mL (495.50mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C15H12N2O2

SMILES

Cn1cccc1C=C1C(=O)NC(=O)c2ccccc21

CAS Number

1104546-89-5

Target & IC50

PARP1: ic50 44.67nM

In Vitro

BYK204165 displayed 100-fold selectivity for PARP-1[1].

Product Categories/Family for BYK204165, inhibitor

Chromatin/Epigenetic; PARP; DNA Damage/DNA Repair

Product References and Citations for BYK204165, inhibitor

Eltze T, Boer R, Wagner T, et al. Imidazoquinolinone, imidazopyridine, and isoquinolindione derivatives as novel and potent inhibitors of the poly(ADP-ribose) polymerase (PARP): a comparison with standard PARP inhibitors.[J]. molecular pharmacology, 2008, 74(6):1587-1598.

Other Notes

Small volumes of BYK204165, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BYK204165 purchase

MBS5758758 is an inhibitor targeting BYK204165.