8-Bromoguanosine Inhibitor

8-Bromoguanosine is a brominated derivative of guanosine. It is activate lymphocytes through an intracellular mechanism to exert immunostimulatory effects.

Selma Giorgio, Sandra C. Bara£o. Intracellular Leishmania amazonensis killing induced by the guanine nucleoside 8-bromoguanosine[J]. Rev Inst Med Trop Sao Paulo, 1998, 40(4):237-240.
Selma Giorgio, Sandra C. Bara£o. Intracellular Leishmania amazonensis killing induced by the guanine nucleoside 8-bromoguanosine[J]. Rev Inst Med Trop Sao Paulo, 1998, 40(4):237-240.
Suzuki T, Kosaka A, Inukai M. Formation of 8-S-l-cysteinylguanosine from 8-bromoguanosine and cysteine[J]. Bioorganic & Medicinal Chemistry Letters, 2013, 23(13):3864-3867.
Suzuki T, Kosaka A, Inukai M. Formation of 8-S-l-cysteinylguanosine from 8-bromoguanosine and cysteine[J]. Bioorganic & Medicinal Chemistry Letters, 2013, 23(13):3864-3867.

Small volumes of 8-Bromoguanosine, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5758783 is an inhibitor targeting 8-Bromoguanosine.