FT113 Inhibitor

Name: FT113 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5758804
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5758804

FT113 is a novel potent inhibitor of fatty acid synthase (fasn, IC50 : 213nM), and exhibits anti-cancer activity More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

FT113, Inhibitor

Full Product Name

FT113

Product Gene Name

FT113, inhibitor

Form/Format

Solid. Powder

Purity/Purification

97.68%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

409.41

Solubility

DMSO: 62.5mg/mL (152.66mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C22H20FN3O4

SMILES

OC1(CC1)C(=O)N1CCN(CC1)C(=O)c1ccc(cc1)-c1nc2ccc(F)cc2o1

CAS Number

1630808-89-7

Target & IC50

fas: ic50 213nM

In Vitro

FT113, a compound with potent biochemical and cellular activity, which translated into excellent activity in in vivo models.Caused 32% and 50% tumor growth inhibition at 25 and 50mg/kg, respectively in mice.

Product Categories/Family for FT113, inhibitor

Metabolism; Fatty Acid Synthase

Product References and Citations for FT113, inhibitor

Martin MW, et al. Discovery and optimization of novel piperazines as potent inhibitors of fatty acid synthase (FASN). Bioorg Med Chem Lett. 2019 Apr 15;29(8):1001-1006.

Other Notes

Small volumes of FT113, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FT113 purchase

MBS5758804 is an inhibitor targeting FT113.