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bpV Inhibitor – (Hopic)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5758807

MBS5758807 is an inhibitor targeting bpV. Also known as bpV (HOpic). bpV (HOpic) is a potent inhibitor of PTEN (IC50 of 14nM). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
bpV (HOpic), Inhibitor
Full Product Name
bpV (HOpic)
Product Gene Name
bpV, inhibitor
Form/Format
Solid. Powder
Purity/Purification
99.86%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
347.24
Solubility
H2O: 69mg/mL (198.71mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C6H4K2NO8V
SMILES
[K+].[K+].OC1=CC=C2N(=C1)|[V+3]|3|4(|[O-][O-]|3)(|[O-][O-]|4)(|[O-]C2=O)=O
CAS Number
722494-26-0
Target & IC50
PTEN: ic50 14nM (Cell-free assay)

Product Categories/Family for bpV, inhibitor

PTEN; Others

Structure of bpV, inhibitor

bpV Inhibitor – Cat# MBS5758807

Product References and Citations for bpV, inhibitor

Dimchev GA, Al-Shanti N, Stewart CE.Phospho-tyrosine phosphatase inhibitor Bpv(Hopic) enhances C2C12 myoblast migration in vitro. Requirement of PI3K/AKT and MAPK/ERK pathways.J Muscle Res Cell Motil. 2013 May;34(2):125-36.
Dimchev GA, Al-Shanti N, Stewart CE.Phospho-tyrosine phosphatase inhibitor Bpv(Hopic) enhances C2C12 myoblast migration in vitro. Requirement of PI3K/AKT and MAPK/ERK pathways.J Muscle Res Cell Motil. 2013 May;34(2):125-36.
Schmid A C, Byrne R D, Ramon Vilar, et al. Bisperoxovanadium compounds are potent PTEN inhibitors[J]. Febs Letters, 2004, 566(1-3):0-38.
Schmid A C, Byrne R D, Ramon Vilar, et al. Bisperoxovanadium compounds are potent PTEN inhibitors[J]. Febs Letters, 2004, 566(1-3):0-38.

Other Notes

Small volumes of bpV, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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