EB-3D Inhibitor

EB-3D is a potent and selective choline kinase alpha 1 (ChoKalpha1) inhibitor(IC50 : 1uM).with anti-cancer activity.

Elena M, Roberta B, Ilaria V, et al. EB-3D a novel choline kinase inhibitor induces deregulation of the AMPK-mTOR Pathway and apoptosis in leukemia T-cells[J]. Biochemical Pharmacology, 2018:S0006295218302727-.
Elena M, Roberta B, Ilaria V, et al. EB-3D a novel choline kinase inhibitor induces deregulation of the AMPK-mTOR Pathway and apoptosis in leukemia T-cells[J]. Biochemical Pharmacology, 2018:S0006295218302727-.
Schiaffino-Ortega S, Baglioni E, Mariotto E, et al. Design, synthesis, crystallization and biological evaluation of new symmetrical biscationic compounds as selective inhibitors of human Choline Kinase alpha1 (ChoKalpha1)[J]. Scientific Reports, 2016, 6:23793.
Schiaffino-Ortega S, Baglioni E, Mariotto E, et al. Design, synthesis, crystallization and biological evaluation of new symmetrical biscationic compounds as selective inhibitors of human Choline Kinase alpha1 (ChoKalpha1)[J]. Scientific Reports, 2016, 6:23793.

Small volumes of EB-3D, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5758809 is an inhibitor targeting EB-3D.