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3,6-Dihydroxyflavone Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5758835

3,6-Dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
3,6-Dihydroxyflavone, Inhibitor
Full Product Name
3,6-Dihydroxyflavone
Form/Format
Solid. Powder
Purity/Purification
99.95%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
254.24
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C15H10O4
SMILES
Oc(cc1)cc(C2=O)c1OC(c1ccccc1)=C2O
CAS Number
108238-41-1
Target & IC50
Others
Cell Research
Cells were cultured in six-well plates until they reached 100% confluence. A vertical or horizontal wound was gently created in monolayers using a 20uL sterile pipette tip. The cells were then washed for 3 times with growth medium to remove the detached cells, and the medium was added with fresh medium treated with 3,6-DHF. Images were captured using an inverted microscope and camera at designed times to assess the inhibition of wound closure[1].

Product References and Citations for 3,6-Dihydroxyflavone, inhibitor

Chen J, Chang H, Peng X, et al. 3,6-dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway[J]. Scientific Reports, 2016, 6:28858.
Chen J, Chang H, Peng X, et al. 3,6-dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway[J]. Scientific Reports, 2016, 6:28858.
Voicescu M, Bandula R. 3,6-diHydroxyflavone/bovine serum albumin interaction in cyclodextrin medium: Absorption and emission monitoring[J]. Spectrochimica Acta Part A Molecular & Biomolecular Spectroscopy, 2015, 138:628-636.
Voicescu M, Bandula R. 3,6-diHydroxyflavone/bovine serum albumin interaction in cyclodextrin medium: Absorption and emission monitoring[J]. Spectrochimica Acta Part A Molecular & Biomolecular Spectroscopy, 2015, 138:628-636.

Other Notes

Small volumes of 3,6-Dihydroxyflavone, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for 3,6-Dihydroxyflavone purchase

MBS5758835 is an inhibitor targeting 3,6-Dihydroxyflavone.
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