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Methotrexate disodium Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5758853

MBS5758853 is an inhibitor targeting Methotrexate disodium. Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor More details

Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Methotrexate disodium, Inhibitor
Full Product Name
Methotrexate disodium
Form/Format
Solid. Powder
Purity/Purification
99.77%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
498.40
Solubility
H2O: 99mg/mL (198.63mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C20H20N8Na2O5
SMILES
CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(C(=O)NC(CCC(=O)[O-])C(=O)[O-])cc1.[Na+].[Na+]
CAS Number
7413-34-5
Target & IC50
hDHFR (dihydrofolate reductase)

Product References and Citations for Methotrexate disodium, inhibitor

Yang W, Xia Y, Fang Y, et al. Selective Cell Penetrating Peptide-Functionalized Polymersomes Mediate Efficient and Targeted Delivery of Methotrexate Disodium to Human Lung Cancer In Vivo[J]. Advanced Healthcare Materials, 2017:1701135.
Yang W, Xia Y, Fang Y, et al. Selective Cell Penetrating Peptide-Functionalized Polymersomes Mediate Efficient and Targeted Delivery of Methotrexate Disodium to Human Lung Cancer In Vivo[J]. Advanced Healthcare Materials, 2017:1701135.
Yang W, Zou Y, Meng F, et al. Efficient and Targeted Suppression of Human Lung Tumor Xenografts in Mice with Methotrexate Sodium Encapsulated in All-Function-in-One Chimeric Polymersomes[J]. Advanced Materials, 2016, 28(37):8234-8239.
Yang W, Zou Y, Meng F, et al. Efficient and Targeted Suppression of Human Lung Tumor Xenografts in Mice with Methotrexate Sodium Encapsulated in All-Function-in-One Chimeric Polymersomes[J]. Advanced Materials, 2016, 28(37):8234-8239.

Other Notes

Small volumes of Methotrexate disodium, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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