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Iron sucrose Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5758955

MBS5758955 is an inhibitor targeting Iron sucrose. Iron sucrose is treatment,of iron deficiency anemia. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Iron sucrose, Inhibitor
Full Product Name
Iron sucrose
Product Synonym Names
Iron saccharate; Sucroferric oxyhydroxide
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
736.10
Solubility
DMSO: 100mg/mL (135.85mM)
H2O: 100mg/mL (135.85mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C18H24Fe2O24
SMILES
O=C([O-])[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(=O)[O-].O=C([O-])[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(=O)[O-].O=C([O-])[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(=O)[O-].[Fe+3].[Fe+3]
CAS Number
8047-67-4
Target & IC50
Others
Cell Research
in vitro experiments on human peritoneal, the mesothelial effect of elemental iron (in conc. 0.0001-1 mg mL-1) present in Venofer on their viability, growth and synthesis of IL-6 was studied. Additionally we evaluated with a fluorescent probe (2',7'-dichlorodihydro-fluorescein diacatate) generation of reactive oxygen species in cells exposed to iron sucrose. We also measured accumulation of iron in the cytoplasm of mesothelial cells after their in vitro exposure to Venofer[1].

Product References and Citations for Iron sucrose, inhibitor

Breborowicz M, Polubinska A, Tam P, et al. Effect of iron sucrose on human peritoneal mesothelial cells[J]. European Journal of Clinical Investigation, 2003, 33(12):1038-1044.
Breborowicz M, Polubinska A, Tam P, et al. Effect of iron sucrose on human peritoneal mesothelial cells[J]. European Journal of Clinical Investigation, 2003, 33(12):1038-1044.
Kaneva K, Chow E, Rosenfield C G, et al. Intravenous Iron Sucrose for Children With Iron Deficiency Anemia[J]. Journal of Pediatric Hematology/oncology, 2017:1.
Kaneva K, Chow E, Rosenfield C G, et al. Intravenous Iron Sucrose for Children With Iron Deficiency Anemia[J]. Journal of Pediatric Hematology/oncology, 2017:1.

Other Notes

Small volumes of Iron sucrose, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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