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Delafloxacin meglumine Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5758994

MBS5758994 is an inhibitor targeting Delafloxacin meglumine. Delafloxacin meglumine is a broad-spectrum fluoroquinolone antibiotic More details

Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Delafloxacin meglumine, Inhibitor
Full Product Name
Delafloxacin meglumine
Product Synonym Names
ABT492 meglumine; RX-3341 meglumine; WQ-3034 meglumine
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
635.97
Solubility
DMSO: 6.4mg/mL (10.06mM)
H2O: 50mg/mL (78.62mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C25H29ClF3N5O9
SMILES
CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.Nc1nc(c(F)cc1F)-n1cc(C(O)=O)c(=O)c2cc(F)c(N3CC(O)C3)c(Cl)c12
CAS Number
352458-37-8
Target & IC50
Antibiotic
Bacterial
In Vitro
Delafloxacin (3-15.5mg/kg) reduces lung bacterial burden in mouse models of S. aureus and S. pneumoniae lung infection[1]

Product References and Citations for Delafloxacin meglumine, inhibitor

Lepak AJ, et al. In Vivo Pharmacodynamic Target Assessment of Delafloxacin against Staphylococcus aureus, Streptococcus pneumoniae, and Klebsiella pneumoniae in a Murine Lung Infection Model. Antimicrob Agents Chemother. 2016 Jul 22;60(8):4764-9.
Lepak AJ, et al. In Vivo Pharmacodynamic Target Assessment of Delafloxacin against Staphylococcus aureus, Streptococcus pneumoniae, and Klebsiella pneumoniae in a Murine Lung Infection Model. Antimicrob Agents Chemother. 2016 Jul 22;60(8):4764-9.
Mogle, Bryan, T,et al. Clinical review of delafloxacin: a novel anionic fluoroquinolone[J]. Journal of Antimicrobial Chemotherapy, 2018.
Gena K, Kapoor E, Dasgupta A, et al. Delafloxacin meglumine for the treatment,of acute bacterial skin and skin structure infections (ABSSSI).[J]. Drugs of Today, 2018, 54:pags. 657-666.

Other Notes

Small volumes of Delafloxacin meglumine, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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