Fucosterol Inhibitor

Name: Fucosterol Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5759005
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759005

Fucosterol is isolated from E. stolonifera with anti-diabetic, anti-adipogenic and anti-cancer activities. It regulates adipogenesis via modulation of PPARalpha and C/EBPalpha expression. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Fucosterol, Inhibitor

Full Product Name

Fucosterol

Form/Format

Solid. Powder

Purity/Purification

99.68%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

412.70

Solubility

Ethanol: 16.67mg/mL (4.39mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C29H48O

SMILES

CC(C)/C(/CC[C@@H](C)[C@@H](CC1)[C@@](C)(CC2)[C@@H]1[C@H]1[C@H]2[C@@](C)(CC[C@@H](C2)O)C2=CC1)=C/C

CAS Number

17605-67-3

Target & IC50

PPARalpha

Cell Research

Cell Line: 3T3-L1 adipocytes. Concentration: 0uM; 25uM; 50uM. Incubation Time: 7 days [1]

In Vitro

Fucosterol (p.o.; 30mg/kg) causes a significant decrease in serum glucose concentrations and exhibits inhibition of sorbitol accumulations in the lenses [2].

Product Categories/Family for Fucosterol, inhibitor

Metabolism; PPAR

Product References and Citations for Fucosterol, inhibitor

Jung HA, et al. Anti-adipogenic activity of the edible brown alga Ecklonia stolonifera and its constituent fucosterol in 3T3-L1 adipocytes. Arch Pharm Res. 2014 Jun;37(6):713-20.
Jung HA, et al. Anti-adipogenic activity of the edible brown alga Ecklonia stolonifera and its constituent fucosterol in 3T3-L1 adipocytes. Arch Pharm Res. 2014 Jun;37(6):713-20.
Lee YS, et al. Anti-diabetic activities of fucosterol from Pelvetia siliquosa. Arch Pharm Res. 2004 Nov;27(11):1120-2.
Lee YS, et al. Anti-diabetic activities of fucosterol from Pelvetia siliquosa. Arch Pharm Res. 2004 Nov;27(11):1120-2.
Khanavi M, et al. Cytotoxicity of fucosterol containing fraction of marine algae against breast and colon carcinoma cell line. Pharmacogn Mag. 2012 Jan;8(29):60-4.
Khanavi M, et al. Cytotoxicity of fucosterol containing fraction of marine algae against breast and colon carcinoma cell line. Pharmacogn Mag. 2012 Jan;8(29):60-4.
Caamal-Fuentes E, et al. Cytotoxic and antiproliferative constituents from Dictyota ciliolata, Padina sanctae-crucis and Turbinaria tricostata. Pharm Biol. 2014 Oct;52(10):1244-8.
Caamal-Fuentes E, et al. Cytotoxic and antiproliferative constituents from Dictyota ciliolata, Padina sanctae-crucis and Turbinaria tricostata. Pharm Biol. 2014 Oct;52(10):1244-8.

Other Notes

Small volumes of Fucosterol, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Fucosterol purchase

MBS5759005 is an inhibitor targeting Fucosterol.