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Visnagin Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759019

Visnagin has acute hypotensive, anti-inflammatory, and neuroprotective effects, it protects against doxorubicin-induced cardiomyopathy through modulation of mitochondrial malate dehydrogenase. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Visnagin, Inhibitor
Full Product Name
Visnagin
Form/Format
Solid. Powder
Purity/Purification
99.87%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
230.22
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C13H10O4
SMILES
CC(Oc1cc(occ2)c2c(OC)c11)=CC1=O
CAS Number
82-57-5
Target & IC50
Others
In Vitro
Visnagin can relax aortae previously contracted by noradrenaline, and weakly inhibit the hydrolytic activity of the cyclic nucleotide phosphodiesterase (PDE) isozymes (PDE5, PDE4, PDE3, cyclic GMP activated PDE2 and PDE1).

Structure of Visnagin, inhibitor

Visnagin Inhibitor – Cat# MBS5759019

Product References and Citations for Visnagin, inhibitor

Radim Vrzal, et al. Khellin and Visnagin Differentially Modulate AHR Signaling and Downstream CYP1A Activity in Human Liver Cells. PLoS One. 2013 Sep 19;8(9):e74917.
Radim Vrzal, et al. Khellin and Visnagin Differentially Modulate AHR Signaling and Downstream CYP1A Activity in Human Liver Cells. PLoS One. 2013 Sep 19;8(9):e74917.
Min-Soo Kwon, et al. Neuroprotective Effect of Visnagin on Kainic Acid-induced Neuronal Cell Death in the Mice Hippocampus.
Min-Soo Kwon, et al. Neuroprotective Effect of Visnagin on Kainic Acid-induced Neuronal Cell Death in the Mice Hippocampus. Korean J Physiol Pharmacol. 2010 Oct;14(5):257-63.
J Duarte, et al. Cardiovascular Effects of Visnagin on Rats. Planta Med. 2000 Feb;66(1):35-9.
J Duarte, et al. Cardiovascular Effects of Visnagin on Rats. Planta Med. 2000 Feb;66(1):35-9.

Other Notes

Small volumes of Visnagin, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Visnagin purchase

MBS5759019 is an inhibitor targeting Visnagin.
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