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Enzalutamide carboxylic acid Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759031

MBS5759031 is an inhibitor targeting Enzalutamide carboxylic acid. Enzalutamide carboxylic acid is an antagonist of androgen receptor (AR). More details

Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Enzalutamide carboxylic acid, Inhibitor
Full Product Name
Enzalutamide carboxylic acid
Form/Format
Solid. Powder
Purity/Purification
98.29%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
451.40
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C20H13F4N3O3S
SMILES
CC1(C)N(C(=S)N(C1=O)c1ccc(C#N)c(c1)C(F)(F)F)c1ccc(C(O)=O)c(F)c1
CAS Number
1242137-15-0
Target & IC50
Androgen Receptor

Product References and Citations for Enzalutamide carboxylic acid, inhibitor

Scott, Lesley J. Enzalutamide: A Review in Castration-Resistant Prostate Cancer[J]. Drugs, 2018.
van Nuland M, et al. Exposure-Response Assessment of Enzalutamide and Its Major Metabolites in a Real-World Cohort of Patients with Metastatic Castration-Resistant Prostate Cancer. Pharmacotherapy. 2019 Dec;39(12):1137-1145.
Clinical Pharmacokinetic Studies of Enzalutamide[J]. Clinical Pharmacokinetics, 2015, 54(10):1043-1055.

Other Notes

Small volumes of Enzalutamide carboxylic acid, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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