BRD3308 Inhibitor

Name: BRD3308 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5759044
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759044

BRD3308 is a highly selective inhibitor of HDAC3(IC50 of 54nM), attenuating PE-mediated phosphorylation of ERK but not JNK. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

BRD3308, Inhibitor

Full Product Name

BRD3308

Product Gene Name

BRD3308, inhibitor

Form/Format

Solid. Powder

Purity/Purification

97.12%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

287.29

Solubility

DMSO: 52mg/mL (181mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C15H14FN3O2

SMILES

CC(=O)Nc1ccc(cc1)C(=O)Nc1ccc(F)cc1N

CAS Number

1550053-02-5

Target & IC50

HDAC3: ic50 29nM (Ki)
HDAC1: ic50 5100nM (Ki)
HDAC2: ic50 6300nM (Ki)

Product Categories/Family for BRD3308, inhibitor

Chromatin/Epigenetic; DNA Damage/DNA Repair

Product References and Citations for BRD3308, inhibitor

Lundh M, et al. Histone deacetylase 3 inhibition improves glycaemia and insulin secretion in obese diabetic rats. Diabetes Obes Metab. 2015 Jul;17(7):703-7.
Lundh M, et al. Histone deacetylase 3 inhibition improves glycaemia and insulin secretion in obese diabetic rats. Diabetes Obes Metab. 2015 Jul;17(7):703-7.
Wagner FF, et al. An Isochemogenic Set of Inhibitors To Define the Therapeutic Potential of Histone Deacetylases in beta-Cell Protection. ACS Chem Biol. 2016 Feb 19;11(2):363-74.
Wagner FF, et al. An Isochemogenic Set of Inhibitors To Define the Therapeutic Potential of Histone Deacetylases in beta-Cell Protection. ACS Chem Biol. 2016 Feb 19;11(2):363-74.

Other Notes

Small volumes of BRD3308, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BRD3308 purchase

MBS5759044 is an inhibitor targeting BRD3308.