RHC80267 Inhibitor – RHC 80267

MBS5759047 is an inhibitor targeting RHC80267. Also known as RHC 80267. RHC 80267 is a selective inhibitor of DAGL (IC50 : 4uM in canine platelets)

Ghisdal P, et al. The diacylglycerol lipase inhibitor RHC-80267 potentiates the relaxation to acetylcholine in rat mesenteric artery by anti-cholinesterase action. Eur J Pharmacol. 2005 Jul 4;517(1-2):97-102.
Suzuki H, Kito Y, Fukuta H, et al. Effects of RHC-80267, an Inhibitor of Diacylglycerol Lipase, on Excitation of Circular Smooth Muscle of the Guinea-Pig Gastric Antrum[J]. j smooth muscle res, 2003, 38(6):153-164.
Sutherland CA, et al. Relative activities of rat and dog platelet phospholipase A2 and diglyceride lipase. Selective inhibition of diglyceride lipase by RHC 80267. J Biol Chem. 1982 Dec 10;257(23):14006-10.

Small volumes of RHC80267, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.