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NL-1 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759115

MBS5759115 is an inhibitor targeting NL-1. NL-1 is a mitoNEET inhibitor with antileukemic effect. More details

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Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NL-1, Inhibitor
Full Product Name
NL-1
Product Gene Name
NL-1, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.42%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
335.46
Solubility
DMSO: 250mg/mL (745.25mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C18H25NO3S
SMILES
CC(C)(C)c1cc(CC2SC(=O)NC2=O)cc(c1O)C(C)(C)C
CAS Number
188532-26-5
Target & IC50
mitoNEET
In Vitro
NL-1 showed antileukemic activity in an in vivo mouse ALL model

Product Categories/Family for NL-1, inhibitor

Autophagy; Autophagy; Metabolic Enzyme/Protease

Structure of NL-1, inhibitor

NL-1 Inhibitor – Cat# MBS5759115

Product References and Citations for NL-1, inhibitor

Geldenhuys WJ, et al. The MitoNEET Ligand NL-1 Mediates Antileukemic Activity in Drug-Resistant B-Cell Acute Lymphoblastic Leukemia. J Pharmacol Exp Ther. 2019 Jul;370(1):25-34.

Other Notes

Small volumes of NL-1, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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