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Lycobetaine acetate Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759141

Lycobetaine acetate is a potential biofungicide against Penicillium roqueforti and Aspergillus niger.2. Ungeremine have strong antibacterial activity against Flavobacterium columnare More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Lycobetaine acetate, Inhibitor
Full Product Name
Lycobetaine acetate
Product Synonym Names
Oxylycorine
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
325.3
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C18H15NO5
SMILES
CC([O-])=O.Oc1cc2CC[n+]3cc4cc5OCOc5cc4c(c1)c23
CAS Number
61221-41-8
Target & IC50
Others
Cell Research
The cytotoxicity, ferroptotic and necroptotic cell death were determined by the resazurin reduction assay. Caspase activation was evaluated using the caspase-Glo assay. Flow cytometry was applied for the analysis of cell cycle analysis (PI staining), apoptosis (annexin V/PI staining), mitochondrial membrane potential (MMP) (JC-1) and reactive oxygen species (ROS) (H2DCFH-DA). Apoptotic, necroptotic and autophagic markers were determined by Western blotting. CCRF-CEM leukemia cells were used for all mechanistic studies[1].

Product References and Citations for Lycobetaine acetate, inhibitor

Armelle T Mbaveng, Gabin T M Bitchagno, Victor Kuete,et al.Cytotoxicity of Ungeremine Towards Multi-Factorial Drug Resistant Cancer Cells and Induction of Apoptosis, Ferroptosis, Necroptosis and Autophagy.Phytomedicine. 2019 Jul;60:152832.
Armelle T Mbaveng, Gabin T M Bitchagno, Victor Kuete,et al.Cytotoxicity of Ungeremine Towards Multi-Factorial Drug Resistant Cancer Cells and Induction of Apoptosis, Ferroptosis, Necroptosis and Autophagy.Phytomedicine. 2019 Jul;60:152832.
Kevin K Schrader, Fabiana Avolio, Anna Andolfi.et alUngeremine and Its Hemisynthesized Analogues as Bactericides Against Flavobacterium Columnare.J Agric Food Chem. 2013 Feb 13;61(6):1179-83.
Kevin K Schrader, Fabiana Avolio, Anna Andolfi.et alUngeremine and Its Hemisynthesized Analogues as Bactericides Against Flavobacterium Columnare.J Agric Food Chem. 2013 Feb 13;61(6):1179-83.

Other Notes

Small volumes of Lycobetaine acetate, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Lycobetaine acetate purchase

MBS5759141 is an inhibitor targeting Lycobetaine acetate.
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