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Rifamycin S Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759152

Rifamycin S is a potent DNA-dependent RNA polymerase inhibitor,is a quinone and an antibiotic agnet against Gram-positive bacteria More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Rifamycin S, Inhibitor
Full Product Name
Rifamycin S
Form/Format
Solid. Powder
Purity/Purification
98.76%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
695.75
Solubility
DMSO: 250mg/mL (359.32mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C37H45NO12
SMILES
CO[C@H]1\C=C\O[C@@]2(C)Oc3c(C2=O)c2C(=O)C=C(NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)C(=O)c2c(O)c3C
CAS Number
13553-79-2
Target & IC50
Bacterial
ROS
In Vitro
rifamycin S and rifabutin can interact with rat liver microsomes to undergo redox-cycling, with the subsequent production of hydroxyl radicals when iron complexes are present[1]

Product References and Citations for Rifamycin S, inhibitor

Rao DN, et al. A comparative study of the redox-cycling of a quinone (rifamycin S) and a quinonimine (rifabutin) antibiotic by rat liver microsomes. Free Radic Biol Med. 1997;22(3):439-46.
Rao DN, et al. A comparative study of the redox-cycling of a quinone (rifamycin S) and a quinonimine (rifabutin) antibiotic by rat liver microsomes. Free Radic Biol Med. 1997;22(3):439-46.
Huang H, et al. Rifamycin S and its geometric isomer produced by a newly found actinomycete,microMonospora rifamycinica. Antonie Van Leeuwenhoek. 2009 Feb;95(2):143-8.
Huang H, et al. Rifamycin S and its geometric isomer produced by a newly found actinomycete,microMonospora rifamycinica. Antonie Van Leeuwenhoek. 2009 Feb;95(2):143-8.

Other Notes

Small volumes of Rifamycin S, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Rifamycin S purchase

MBS5759152 is an inhibitor targeting Rifamycin S.
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