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SB-200646 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759161

MBS5759161 is an inhibitor targeting SB-200646. SB-200646 is a selective and potent antagonist of 5-HT2B/5-HT2C receptor More details

Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SB-200646, Inhibitor
Full Product Name
SB-200646
Product Gene Name
Form/Format
Solid. Powder
Purity/Purification
99.80%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
266.30
Solubility
DMSO: 53mg/mL (199.02mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C15H14N4O
SMILES
Cn1ccc2cc(NC(=O)Nc3cccnc3)ccc12
CAS Number
143797-63-1
Target & IC50
5-HT2B Receptor: ic50 7.5 (pKi)
5-HT2C Receptor: ic50 6.9 (pKi)
5-HT2A Receptor: ic50 5.2 (pKi)

Product Categories/Family for SB-200646, inhibitor

Structure of SB-200646, inhibitor

SB-200646 Inhibitor – Cat# MBS5759161

Product References and Citations for SB-200646, inhibitor

Kennett GA, et al. In vivo properties of SB 200646A, a 5-HT2C/2B receptor antagonist. Br J Pharmacol. 1994 Mar;111(3):797-802.
Kennett GA, et al. In vivo properties of SB 200646A, a 5-HT2C/2B receptor antagonist. Br J Pharmacol. 1994 Mar;111(3):797-802.
Blackburn TP, et al. The acute and chronic administration of the 5-HT(2B/2C) receptor antagonist SB-200646A significantly alters the activity of spontaneously active midbrain dopamine neurons in the rat: An in vivo extracellular single cell study. Synapse. 2006 Jun 15;59(8):502-12.
Blackburn TP, et al. The acute and chronic administration of the 5-HT(2B/2C) receptor antagonist SB-200646A significantly alters the activity of spontaneously active midbrain dopamine neurons in the rat: An in vivo extracellular single cell study. Synapse. 2006 Jun 15;59(8):502-12.

Other Notes

Small volumes of SB-200646, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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