GSK5182 Inhibitor

Name: GSK5182 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5759174
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759174

GSK5182 is a highly selective inverse estrogen-related receptor gamma agonist (IC50 : 79nM) More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GSK5182, Inhibitor

Full Product Name

GSK5182

Product Gene Name

GSK5182, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

417.55

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C27H31NO3

SMILES

CN(C)CCOc1ccc(cc1)C(\c1ccc(O)cc1)=C(\CCCO)c1ccccc1

CAS Number

877387-37-6

Target & IC50

ERRgamma

Cell Research

Cell Line:The human hepatoma cell line PLC/PRF/5. Concentration:0uM, 10uM, 20uM. Incubation Time:0 hour, 24 hours, 48 hours, 72 hours

Product Categories/Family for GSK5182, inhibitor

Endocrinology/Hormones; Estrogen/progestogen Receptor

Product References and Citations for GSK5182, inhibitor

Kim JH, et al. Estrogen-related receptor gamma is upregulated in liver cancer and its inhibition suppresses livercancer cell proliferation via induction of p21 and p27. Exp Mol Med. 2016 Mar 4;48:e213.
Kim JH, et al. Estrogen-related receptor gamma is upregulated in liver cancer and its inhibition suppresses livercancer cell proliferation via induction of p21 and p27. Exp Mol Med. 2016 Mar 4;48:e213.
Kim DK, et al. Inverse agonist of nuclear receptor ERRgamma mediates antidiabetic effect through inhibition of hepatic gluconeogenesis. Diabetes. 2013 Sep;62(9):3093-10
Kim DK, et al. Inverse agonist of nuclear receptor ERRgamma mediates antidiabetic effect through inhibition of hepatic gluconeogenesis. Diabetes. 2013 Sep;62(9):3093-102.

Other Notes

Small volumes of GSK5182, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GSK5182 purchase

MBS5759174 is an inhibitor targeting GSK5182.