GKT136901 Inhibitor

Name: GKT136901 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5759211
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759211

GKT136901 is an inhibitor of NOX1/4.It acts as Selective and Direct Scavenger of Peroxynitrite More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GKT136901, Inhibitor

Full Product Name

GKT136901

Product Gene Name

GKT136901, inhibitor

Product Synonym Names

AK120765

Form/Format

Solid. Powder

Purity/Purification

98.29%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

366.8

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C19H15ClN4O2

SMILES

Cc1n(Cc2ccccn2)c(=O)cc2[nH]n(-c3ccccc3Cl)c(=O)c12

CAS Number

955272-06-7

Target & IC50

NOX1

In Vitro

GKT136901 is a novel NOX-1/4 inhibitor with potential application in the areas of diabetic nephropathy, stroke, or neurodegeneration[1]

Product Categories/Family for GKT136901, inhibitor

Immunology/Inflammation; NADPH-oxidase

Product References and Citations for GKT136901, inhibitor

S Schildknecht, A Weber, H R Gerding. The NOX1/4 Inhibitor GKT136901 as Selective and Direct Scavenger of Peroxynitrite.Curr Med Chem. 2014;21(3):365-76.
S Schildknecht, A Weber, H R Gerding. The NOX1/4 Inhibitor GKT136901 as Selective and Direct Scavenger of Peroxynitrite.Curr Med Chem. 2014;21(3):365-76.
Fiona Augsburger, Aleksandra Filippova, Delphine Rasti.Pharmacological Characterization of the Seven Human NOX Isoforms and Their Inhibitors.Redox Biol. 2019 Sep;26:101272.
Fiona Augsburger, Aleksandra Filippova, Delphine Rasti.Pharmacological Characterization of the Seven Human NOX Isoforms and Their Inhibitors.Redox Biol. 2019 Sep;26:101272.

Other Notes

Small volumes of GKT136901, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GKT136901 purchase

MBS5759211 is an inhibitor targeting GKT136901.