TED-347 Inhibitor

Name: TED-347 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5759221
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759221

TED-347 is an irreversible and covalent inhibitor of TEAD4-Yap1 protein-protein interaction(EC50 of 5.9 uM), and inhibits glioblastoma cell viability. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TED-347, Inhibitor

Full Product Name

TED-347

Product Gene Name

TED-347, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

313.70

Solubility

DMSO: 64mg/mL (204.02mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C15H11ClF3NO

SMILES

FC(F)(F)c1cccc(Nc2ccccc2C(=O)CCl)c1

CAS Number

2378626-29-8

Target & IC50

TEAD4-Yap1: ic50 5.9uM (EC50)

Product Categories/Family for TED-347, inhibitor

Stem Cell/Wnt

Product References and Citations for TED-347, inhibitor

Khuchtumur Bum-Erdene, et al. Small-Molecule Covalent Modification of Conserved Cysteine Leads to Allosteric Inhibition of the TEAD-Yap Protein-Protein Interaction. Cell Chem Biol. 2019 Mar 21;26(3):378-389.e13.

Other Notes

Small volumes of TED-347, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TED-347 purchase

MBS5759221 is an inhibitor targeting TED-347.