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TLK117 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759223

TLK117 selective inhibits Glutathione S-transferase P1-1 (GSTP1-1)(Ki of 0.4uM for GSTP). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
TLK117, Inhibitor
Full Product Name
TLK117
Product Gene Name
TLK117, inhibitor
Product Synonym Names
TER117
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
473.54
Solubility
DMSO: 150mg/mL (316.76mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C23H27N3O6S
SMILES
O=C(O)[C@@H](C1=CC=CC=C1)NC([C@@H](NC(CC[C@H](N)C(O)=O)=O)CSCC2=CC=CC=C2)=O
CAS Number
152684-53-2
Target & IC50
Others

Structure of TLK117, inhibitor

TLK117 Inhibitor – Cat# MBS5759223

Product References and Citations for TLK117, inhibitor

The human glutathione transferase P1-1 specific inhibitor TER 117 designed for overcomingcytostatic-drug resistance is also a strong inhibitor of glyoxalase I. Mol Pharmacol. 2000 Mar;57(3):619-24.
The human glutathione transferase P1-1 specific inhibitor TER 117 designed for overcomingcytostatic-drug resistance is also a strong inhibitor of glyoxalase I. Mol Pharmacol. 2000 Mar;57(3):619-24.
McMillan DH, et al. Attenuation of lung fibrosis in mice with a clinically relevant inhibitor of glutathione-S-transferase eta. JCI Insight. 2016 Jun 2;1(8). pii: e85717.
McMillan DH, et al. Attenuation of lung fibrosis in mice with a clinically relevant inhibitor of glutathione-S-transferase eta. JCI Insight. 2016 Jun 2;1(8). pii: e85717.

Other Notes

Small volumes of TLK117, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TLK117 purchase

MBS5759223 is an inhibitor targeting TLK117.
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