Clobenpropit dihydrobromide Inhibitor

Clobenpropit dihydrobromide is a potent antagonist and inverse agonist of histamine HR (histamine HLR,pEC50 of 8.07)

Mena-Avila E, et al. Clobenpropit, a histamine H receptor antagonist/inverse agonist, inhibits [3H]-dopamine uptake by human neuroblastoma SH-SY5Y cells and rat brain synaptosomes. Pharmacol Rep. 2018 Feb;70(1):146-155.
Mena-Avila E, et al. Clobenpropit, a histamine H receptor antagonist/inverse agonist, inhibits [3H]-dopamine uptake by human neuroblastoma SH-SY5Y cells and rat brain synaptosomes. Pharmacol Rep. 2018 Feb;70(1):146-155.
Esbenshade TA, et al. Two novel and selective nonimidazole histamine H receptor antagonists A-304121 and A-317920: I. In vitro pharmacological effects. J Pharmacol Exp Ther. 2003 Jun;305(3):887-96.
Esbenshade TA, et al. Two novel and selective nonimidazole histamine H receptor antagonists A-304121 and A-317920: I. In vitro pharmacological effects. J Pharmacol Exp Ther. 2003 Jun;305(3):887-96.

Small volumes of Clobenpropit dihydrobromide, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5759236 is an inhibitor targeting Clobenpropit dihydrobromide.