TC-I2000 Inhibitor

Name: TC-I2000 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5759245
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759245

TC-I2000 is an TRPM8 channel blocker. Inhibits icilin-induced TRPM8 channel activation in rTRPM8-expressing CHO cells with IC50 of 53nM. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TC-I2000, Inhibitor

Full Product Name

TC-I2000

Product Gene Name

TC-I2000, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.87%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

414.40

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C23H18F4N2O

SMILES

Fc1ccc(NC(=O)N2CCc3ccccc3C2c2ccc(cc2)C(F)(F)F)cc1

CAS Number

1159996-20-9

Target & IC50

TRPM8

Product Categories/Family for TC-I2000, inhibitor

Membrane transporter/Ion channel

Product References and Citations for TC-I2000, inhibitor

Tamayo N A, Bo Y, Gore V, et al. Fused Piperidines as a Novel Class of Potent and Orally Available Transient Receptor Potential Melastatin Type 8 (TRPM8) Antagonists[J]. Journal of Medicinal Chemistry, 2012, 55(4):1593-1611.

Other Notes

Small volumes of TC-I2000, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TC-I2000 purchase

MBS5759245 is an inhibitor targeting TC-I2000.