Spinorphin Inhibitor

Name: Spinorphin Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5759250
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759250

Spinorphin is a heptapeptide, and is a potent enkephalin-degrading enzymes inhibitor. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Spinorphin, Inhibitor

Full Product Name

Spinorphin

Form/Format

Solid. Powder

Purity/Purification

100.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

877.00

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C45H64N8O10

SMILES

CC(C)C[C@H](N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CNC2=CC=CC=C12)C(=O)N[C@@H]([C@@H](C)O)C(O)=O

CAS Number

137201-62-8

Target & IC50

enkephalin degrading enzymes

In Vitro

Spinorphin significantly inhibited the functions of polymorphonuclear neutrophils (PMNs) by suppressing the binding of fMLF to its receptor on PMNs. Further, this inhibitor suppressed the carrageenan-induced accumulation of PMN in mouse air pouches after intravenous administration. These results indicate that spinorphin may be an endogenous anti-inflammatory regulator. The possible role of spinorphin and its analog as regulators in pain and inflammation will be discussed[2].

Product Categories/Family for Spinorphin, inhibitor

Endocrinology/Hormones; Opioid Receptor; Neuroscience

Product References and Citations for Spinorphin, inhibitor

Ayar A, Ozcan M, Kemal Tugrul Kuzgun, et al. Spinorphin inhibits membrane depolarization- and capsaicin-induced intracellular calcium signals in rat primary nociceptive dorsal root ganglion neurons in culture[J]. Journal of Receptor Research, 2015, 35(6):550-558.
Ayar A, Ozcan M, Kemal Tugrul Kuzgun, et al. Spinorphin inhibits membrane depolarization- and capsaicin-induced intracellular calcium signals in rat primary nociceptive dorsal root ganglion neurons in culture[J]. Journal of Receptor Research, 2015, 35(6):550-558.
YAMAMOTO,Y. Spinorphin as an endogenous inhibitor of enkephalin-degrading enzymes: roles in pain and inflammation.[J]. Current Protn & Peptide ence, 2002, 3(6):-.
YAMAMOTO,Y. Spinorphin as an endogenous inhibitor of enkephalin-degrading enzymes: roles in pain and inflammation.[J]. Current Protn & Peptide ence, 2002, 3(6):-.

Other Notes

Small volumes of Spinorphin, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Spinorphin purchase

MBS5759250 is an inhibitor targeting Spinorphin.