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Olmutinib Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759255

MBS5759255 is an inhibitor targeting Olmutinib. Olmutinib is a Novel Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor More details

Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Olmutinib, Inhibitor
Full Product Name
Olmutinib
Product Synonym Names
BI1482694; HM61713
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
486.60
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C26H26N6O2S
SMILES
CN1CCN(CC1)c1ccc(cc1)Nc1nc2c(c(n1)Oc1cccc(c1)NC(=O)C=C)scc2
CAS Number
1802181-20-9
Target & IC50
EGFR

Product References and Citations for Olmutinib, inhibitor

Zhang W, Fan Y F, Cai C Y, et al. Olmutinib (BI1482694/HM61713), a Novel Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, Reverses ABCG2-Mediated Multidrug Resistance in Cancer Cells[J]. Frontiers in Pharmacology, 2018, 9.
Zhang W, Fan Y F, Cai C Y, et al. Olmutinib (BI1482694/HM61713), a Novel Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, Reverses ABCG2-Mediated Multidrug Resistance in Cancer Cells[J]. Frontiers in Pharmacology, 2018, 9.
Zhang Z, Fu L, Guo X, et al. Olmutinib (HM61713) reversed multidrug resistance by inhibiting the activity of ATPbinding cassette subfamily G member 2 in vitro and in vivo[J]. 药A-¦A-¦æŠ¥(è‹+/-æ-‡ç‰ˆ), 2018, 008(004):563-574.
Zhang Z, Fu L, Guo X, et al. Olmutinib (HM61713) reversed multidrug resistance by inhibiting the activity of ATPbinding cassette subfamily G member 2 in vitro and in vivo[J]. 2018, 008(004):563-574.

Other Notes

Small volumes of Olmutinib, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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