SKIV Inhibitor – SKI V

Name: SKIV Inhibitor; SKI V; MyBioSource
Brand: MyBioSource
SKU: MBS5759256
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759256

SKI V is a potent and noncompetitive non-lipid sphingosine kinase (SPHK; SK) inhibitor (GST-hSK,IC50 : 2uM), and is a PI3K inhibitor(hPI3k,IC50 : 6uM), induces apoptosis and has antitumor activity More details

Please Inquire

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SKI V (SKIV), Inhibitor

Full Product Name

SKI V

Product Gene Name

SKIV, inhibitor

Form/Format

Solid. Powder

Purity/Purification

99.62%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

254.24

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C15H10O4

SMILES

Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O

CAS Number

24418-86-8

Target & IC50

GST-hSK: ic50 2uM
hPI3k: ic50 6uM
ERK2: ic50 80uM

Product Categories/Family for SKIV, inhibitor

GPCR/G Protein; PI3K/Akt/mTOR signaling

Product References and Citations for SKIV, inhibitor

French KJ, et al. Antitumor activity of sphingosine kinase inhibitors. J Pharmacol Exp Ther. 2006 Aug;318(2):596-603.
French KJ, et al. Antitumor activity of sphingosine kinase inhibitors. J Pharmacol Exp Ther. 2006 Aug;318(2):596-603.
French KJ, et al. Discovery and evaluation of inhibitors of human sphingosine kinase. Cancer Res. 2003 Sep 15;63(18):5962-9.
French KJ, et al. Discovery and evaluation of inhibitors of human sphingosine kinase. Cancer Res. 2003 Sep 15;63(18):5962-9.

Other Notes

Small volumes of SKIV, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SKIV purchase

MBS5759256 is an inhibitor targeting SKIV. Also known as SKI V.