LML-134 Inhibitor

Name: LML-134 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5759306
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759306

LML-134 is an inverse agonist of Histamine 3 receptor (H3R)(hH3R cAMP and hH3R bdg with Kis of 0.3nM and 12nM). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

LML-134, Inhibitor

Full Product Name

LML-134

Product Gene Name

LML-134, inhibitor

Form/Format

Solid. Powder

Purity/Purification

99.86%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

375.47

Solubility

DMSO: 7.5mg/mL (19.97mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C19H29N5O3

SMILES

Cn1nc(ccc1=O)N1CCC(CC1)OC(=O)N1CCN(CC1)C1CCC1

CAS Number

1542135-76-1

Target & IC50

hH3R cAMP: ic50 0.3nM (ki)
hH3R bdg: ic50 12nM (ki)
H3 receptor

Product Categories/Family for LML-134, inhibitor

GPCR/G Protein; Immunology/Inflammation; Neuroscience

Product References and Citations for LML-134, inhibitor

Troxler T, et al. The Discovery of LML134, a histamine H Receptor Inverse Agonist for the Clinical treatment,of Excessive Sleep Disorders. ChemMedChem. 2019 Jul 3;14(13):1238-1247.

Other Notes

Small volumes of LML-134, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LML-134 purchase

MBS5759306 is an inhibitor targeting LML-134.