BI-409306 Inhibitor

BI-409306 is a potent and selective inhibitor of PDE9A (IC50 of 52nM), and can be used in the research of memory

Cornelia Dorner-Ciossek, R. Giovannini, Holger Rosenbrock. BI 409306, A NOVEL PHOSPHODIESTERASE 9A INHIBITOR, PART I: POTENCY, SELECTIVITY AND IN-VITRO FUNCTIONAL CHARACTERIZATION ON SYNAPTIC PLASTICITY[C]// International Congress on Schizophrenia Research. 2015.
Cornelia Dorner-Ciossek, R. Giovannini, Holger Rosenbrock. BI 409306, A NOVEL PHOSPHODIESTERASE 9A INHIBITOR, PART I: POTENCY, SELECTIVITY AND IN-VITRO FUNCTIONAL CHARACTERIZATION ON SYNAPTIC PLASTICITY[C]// International Congress on Schizophrenia Research. 2015.
Moschetti V, Kim M, Sand M, et al. The safety, tolerability and pharmacokinetics of BI 409306, a novel and potent PDE9 inhibitor: Overview of three Phase I randomised trials in healthy volunteers[J]. European Neuropsychopharmacology, 2018:S0924977X18300233.
Moschetti V, Kim M, Sand M, et al. The safety, tolerability and pharmacokinetics of BI 409306, a novel and potent PDE9 inhibitor: Overview of three Phase I randomised trials in healthy volunteers[J]. European Neuropsychopharmacology, 2018:S0924977X18300233.

Small volumes of BI-409306, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5759307 is an inhibitor targeting BI-409306.