Metformin Inhibitor

Name: Metformin Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5759315
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759315

Metformin is an AMP-activated protein kinase (AMPK) activator that improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Metformin, Inhibitor

Full Product Name

Metformin

Product Synonym Names

1,1-Dimethylbiguanide

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

129.16

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C4H11N5

SMILES

CN(C)C(=N)NC(N)=N

CAS Number

657-24-9

Target & IC50

AMPK
Autophagy

In Vitro

Metformin is a first-line drug for the treatment of type 2 diabetes (T2D) and is often prescribed in combination with other drugs to control a patient's blood glucose level and achieve their HbA1c goal.

Product Categories/Family for Metformin, inhibitor

PI3K/Akt/mTOR signaling; Autophagy

Product References and Citations for Metformin, inhibitor

Quaile M P, Melich D H, Jordan H L, et al. Toxicity and toxicokinetics of metformin in rats[J]. Toxicology & Applied Pharmacology, 2010, 243(3):340-347.
Quaile M P, Melich D H, Jordan H L, et al. Toxicity and toxicokinetics of metformin in rats[J]. Toxicology & Applied Pharmacology, 2010, 243(3):340-347.
Xue J, et al. Metformin inhibits growth of eutopic stromal cells from adenomyotic endometrium via AMPK activation and subsequent inhibition of AKT phosphorylation: a possible role in the treatment,of adenomyosis. Reproduction. 2013 Aug 21;146(4):397-406.
Xue J, et al. Metformin inhibits growth of eutopic stromal cells from adenomyotic endometrium via AMPK activation and subsequent inhibition of AKT phosphorylation: a possible role in the treatment,of adenomyosis. Reproduction. 2013 Aug 21;146(4):397-406.
Soraya H, et al. Acute treatment,with metformin improves cardiac function following isoproterenol induced myocardial infarction in rats. Pharmacol Rep. 2012;64(6):1476-84.
Soraya H, et al. Acute treatment,with metformin improves cardiac function following isoproterenol induced myocardial infarction in rats. Pharmacol Rep. 2012;64(6):1476-84.

Other Notes

Small volumes of Metformin, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Metformin purchase

MBS5759315 is an inhibitor targeting Metformin.