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ML318 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759322

ML318 is a biaryl nitrile PvdQ acylase inhibitor (IC50 of 20nM for binding in the acyl-binding site). ML318 inhibits P. aeruginosa (PAO1) with IC50 of 19 uM. ML318 prevents pyoverdine production and limits the growth of P. aeruginosa under iron-limiting… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ML318, Inhibitor
Full Product Name
ML318
Product Gene Name
ML318, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
280.22
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C14H8F4N2
SMILES
Fc1ccc(cc1)C(C#N)c1cccc(n1)C(F)(F)F
CAS Number
1610516-67-0
Target & IC50
PvdQ acylase

Structure of ML318, inhibitor

ML318 Inhibitor – Cat# MBS5759322

Product References and Citations for ML318, inhibitor

Jacqueline M Wurst, et al. Identification of inhibitors of PvdQ, an enzyme involved in the synthesis of the siderophore pyoverdine. ACS Chem Biol. 2014 Jul 18;9(7):1536-44.

Other Notes

Small volumes of ML318, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ML318 purchase

MBS5759322 is an inhibitor targeting ML318.
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