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KCC-07 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759340

KCC-07 is a selective, potent and brain-penetrant inhibitor of methyl-CpG-binding domain protein 2(MBD2) with anticancer activity. KCC-07 prevents binding of MBD2 to methylated DNA and activates brain specific angiogenesis inhibitor 1 (BAI1) inducing… More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KCC-07, Inhibitor
Full Product Name
KCC-07
Product Gene Name
Form/Format
Solid. Powder
Purity/Purification
99.93%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
269.32
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C14H11N3OS
SMILES
Oc1cccc(Nc2nc(cs2)-c2ccccn2)c1
CAS Number
315702-75-1
Target & IC50
MBD2 (methyl-CpG-binding domain protein 2)
Others
Cell Research
KCC-07 treatment Medulloblastomas (MB) cells. Concentration with 10uM and Incubation Time with 72 hours.

Product Categories/Family for KCC-07, inhibitor

Structure of KCC-07, inhibitor

KCC-07 Inhibitor – Cat# MBS5759340

Product References and Citations for KCC-07, inhibitor

Dan Zhu, et al. BAI1 Suppresses Medulloblastoma Formation by Protecting p53 From Mdm2-Mediated Degradation. Cancer Cell. 2018 Jun 11;33(6):1004-1016.e5.

Other Notes

Small volumes of KCC-07, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KCC-07 purchase

MBS5759340 is an inhibitor targeting KCC-07.
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