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Amiflamine Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759374

MBS5759374 is an inhibitor targeting Amiflamine. Amiflamine is an inhibitor of reversible MAO-A. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Amiflamine, Inhibitor
Full Product Name
Amiflamine
Product Synonym Names
4-(dimethylamino)-alpha; 2-dimethylphenethylamine
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
192.301
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C12H20N2
SMILES
c1(c(ccc(c1)N(C)C)[C@@H](N)CC)C
CAS Number
77502-96-6
Target & IC50
MAO-A
In Vitro
Amiflamine was 3 times less potent within noradrenergic neurons than within serotonergic neurons. A brain to plasma ratio of about 20:1 was found for amiflamine and its metabolites. The plasma and the brain concentrations of the N-demethylated metabolite [FLA 788(+)] exceeded that of amiflamine after a single dose, whereas the N,N-demethylated [FLA 668(+)] was found in low concentrations. The effect on MAO-A correlated significantly with the plasma and the brain concentration of FLA 788(+)[2].

Product Categories/Family for Amiflamine, inhibitor

Metabolism; MAO

Structure of Amiflamine, inhibitor

Amiflamine Inhibitor – Cat# MBS5759374

Product References and Citations for Amiflamine, inhibitor

Waldmeier P C. On the reversibility of reversible MAO inhibitors[J]. Naunyn-Schmiedeberg's archives of pharmacology, 1985, 329(3):305-10.
Waldmeier P C. On the reversibility of reversible MAO inhibitors[J]. Naunyn-Schmiedeberg's archives of pharmacology, 1985, 329(3):305-10.
Ask A L, Fagervall I, Jonze M, et al. Effects of acute and repeated administration of amiflamine on monoamine oxidase inhibition in the rat.[J]. Biochemical Pharmacology, 1984, 33(18):2839-2847.
Ask A L, Fagervall I, Jonze M, et al. Effects of acute and repeated administration of amiflamine on monoamine oxidase inhibition in the rat.[J]. Biochemical Pharmacology, 1984, 33(18):2839-2847.

Other Notes

Small volumes of Amiflamine, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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