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pyridostigmine Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759416

Pyridostigmine is an acetylcholinesterase inhibitor that can treat myasthenia gravis by increasing acetylcholine at the postsynaptic motor endplate. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
pyridostigmine, Inhibitor
Full Product Name
pyridostigmine
Product Synonym Names
Pyridostigminum; Regonol; Mestinon-SR; UNII-19QM69HH21; PyridostigmineBromine
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
261.116
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C9H13BrN2O2
SMILES
CN(C)C(=O)Oc1ccc[n+](C)c1.[Br-]
CAS Number
155-97-5
Target & IC50
acetylcholinesterase
In Vitro
Pyridostigmine holds promise for the treatment of various gastrointestinal symptoms in SSc patients, particularly in patients with refractory constipation. Though side effects may limit its use, most patients who experienced benefit chose to continue therapy[1].

Product References and Citations for pyridostigmine, inhibitor

Ahuja N K, Mische L, Clarke J O, et al. Pyridostigmine for the treatment,of gastrointestinal symptoms in systemic sclerosis[J]. Semin Arthritis Rheum, 2018:S0049017217305498.
Ahuja N K, Mische L, Clarke J O, et al. Pyridostigmine for the treatment,of gastrointestinal symptoms in systemic sclerosis[J]. Semin Arthritis Rheum, 2018:S0049017217305498.
Byun J I, Moon J, Kim D Y, et al. Efficacy of single or combined midodrine and pyridostigmine in orthostatic hypotension[J]. Neurology, 2017:10.1212/WNL.0000000000004340.
Byun J I, Moon J, Kim D Y, et al. Efficacy of single or combined midodrine and pyridostigmine in orthostatic hypotension[J]. Neurology, 2017:10.1212/WNL.0000000000004340.

Other Notes

Small volumes of pyridostigmine, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for pyridostigmine purchase

MBS5759416 is an inhibitor targeting pyridostigmine.
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