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PF-06446846 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759429

MBS5759429 is an inhibitor targeting PF-06446846. PF-06446846 is a potent and selective PCSK9 inhibitor More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PF-06446846, Inhibitor
Full Product Name
PF-06446846
Product Gene Name
PF-06446846, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
433.9
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C22H20ClN7O
SMILES
Clc1cccnc1N([C@@H]1CCCNC1)C(=O)c1ccc(cc1)-n1nnc2cccnc12
CAS Number
1632250-49-7
Target & IC50
PCSK9

Structure of PF-06446846, inhibitor

PF-06446846 Inhibitor – Cat# MBS5759429

Product References and Citations for PF-06446846, inhibitor

Lintner N G, Mcclure K F, Donna P, et al. Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain[J]. PLoS Biology, 2017, 15(3):e2001882-.

Other Notes

Small volumes of PF-06446846, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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