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KYP-2047 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759440

MBS5759440 is an inhibitor targeting KYP-2047. KYP-2047 is a very potent, selective Prolyl oligopeptidase (POP) inhibitor. More details

Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KYP-2047, Inhibitor
Full Product Name
KYP-2047
Product Gene Name
Form/Format
Solid. Powder
Purity/Purification
99.70%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
339.44
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C20H25N3O2
SMILES
O=C(CCCc1ccccc1)N1CCC[C@H]1C(=O)N1CCC[C@H]1C#N
CAS Number
796874-99-2
Target & IC50
Prolyl oligopeptidase(pop)

Structure of KYP-2047, inhibitor

KYP-2047 Inhibitor – Cat# MBS5759440

Product References and Citations for KYP-2047, inhibitor

T T Myohanen 1, M J Hannula, R Van Elzen,et al. A prolyl oligopeptidase inhibitor, KYP-2047, reduces alpha-synuclein protein levels and aggregates in cellular and animal models of Parkinson's disease. Br J Pharmacol. 2012 Jun;166(3):1097-113.
T T Myohanen 1, M J Hannula, R Van Elzen,et al. A prolyl oligopeptidase inhibitor, KYP-2047, reduces alpha-synuclein protein levels and aggregates in cellular and animal models of Parkinson's disease. Br J Pharmacol. 2012 Jun;166(3):1097-113.
Jalkanen A J, Leikas J V, Forsberg M M. KYP-2047 Penetrates Mouse Brain and Effectively Inhibits Mouse Prolyl Oligopeptidase[J]. Basic & Clinical Pharmacology & Toxicology, 2014, 114(6):460-463.
Jalkanen A J, Leikas J V, Forsberg M M. KYP-2047 Penetrates Mouse Brain and Effectively Inhibits Mouse Prolyl Oligopeptidase[J]. Basic & Clinical Pharmacology & Toxicology, 2014, 114(6):460-463.

Other Notes

Small volumes of KYP-2047, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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