AZ-32 Inhibitor

Name: AZ-32 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5759443
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759443

AZ32 is an orally bioavailable and blood-brain barrier-penetrating inhibitor of ATM(IC50 of More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

AZ-32, Inhibitor

Full Product Name

AZ-32

Product Gene Name

AZ-32, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

328.37

Solubility

DMSO: 150mg/mL (456.80mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C20H16N4O

SMILES

CNC(=O)c1ccc(cc1)c2cnc3cnc(cn23)c4ccccc4

CAS Number

2288709-96-4

Target & IC50

ATM: ic50 0.31uM (in cell)

Product Categories/Family for AZ-32, inhibitor

DNA Damage/DNA Repair; ATM/ATR; PI3K/Akt/mTOR signaling

Product References and Citations for AZ-32, inhibitor

Karlin J, et al. Orally Bioavailable and Blood-Brain Barrier-Penetrating ATM Inhibitor (AZ32) Radiosensitizes Intracranial Gliomas in Mice. Mol Cancer Ther. 2018 Aug;17(8):1637-1647.

Other Notes

Small volumes of AZ-32, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AZ-32 purchase

MBS5759443 is an inhibitor targeting AZ-32.