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physalin F Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759490

Physalin F is a natural blocker of CaV2.3 (R-type) and CaV2.2 (N-type) voltage-gated calcium channels.It is a secosteroid with potent anti-inflammatory and immunomodulatory activities. Physalin F induces apoptosis of PBMC, decreasing the spontaneous… More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
physalin F, Inhibitor
Full Product Name
physalin F
Form/Format
Solid. Powder
Purity/Purification
99.61%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
526.5
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C28H30O10
SMILES
[H][C@@]12C(=O)[C@]34O[C@]11[C@@](C)(OC(=O)[C@@]1(O)CC[C@@]1([H])[C@@]3([H])C[C@H]3O[C@]33CC=CC(=O)[C@]13C)[C@H]1C[C@]2(C)[C@@]([H])(CO4)C(=O)O1
CAS Number
57423-71-9

Product Categories/Family for physalin F, inhibitor

Product References and Citations for physalin F, inhibitor

Pinto L A, Meira, Cassio S, Villarreal C F, et al. Physalin F, a seco-steroid from Physalis angulata L. has immunosuppressive activity in peripheral blood mononuclear cells from patients with HTLV1-associated myelopathy[J]. Biomedicine & Pharmacotherapy, 2016, 79:129-134.
Ooi K L, Tengku Muhammad T S, Sulaiman S F. Physalin F from Physalis minima L. triggers apoptosis-based cytotoxic mechanism in T-47D cells through the activation caspase-3- and c-myc-dependent pathways[J]. Journal of Ethnopharmacology, 2013, 150(1):382-388.

Other Notes

Small volumes of physalin F, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for physalin F purchase

MBS5759490 is an inhibitor targeting physalin F.
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