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CTPI-2 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759502

CTPI-2 is an inhibitor of mitochondrial citrate carrier SLC25A1 with(KD : 3.5uM). CTPI-2 inhibits glycolysis, PPARgamma, and its downstream target the glucose transporter GLUT4. CTPI-2 exhibits anti-tumor activity.CTPI-2 halts salient alterations of NASH… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CTPI-2, Inhibitor
Full Product Name
CTPI-2
Product Gene Name
CTPI-2, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
391.47
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C23H25N3O3
SMILES
OC(=O)c1ccccc1NS(=O)(=O)c1ccc(Cl)c(c1)[N+]([O-])=O
CAS Number
68003-38-3

Product References and Citations for CTPI-2, inhibitor

Tan M, et al. Inhibition of the mitochondrial citrate carrier, Slc25a1, reverts steatosis, glucose intolerance, and inflammation in preclinical models of NAFLD/NASH. Cell Death Differ. 2020;27(7):2143-2157.
Peng R, Zhang M, Wang H, et al. Advances into Understanding the Vital Role of the Mitochondrial Citrate Carrier (CIC) in Metabolic Diseases, A Review[J]. Pharmacological Research, 2020:105132.

Other Notes

Small volumes of CTPI-2, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CTPI-2 purchase

MBS5759502 is an inhibitor targeting CTPI-2.
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