Infliximab Inhibitor

Infliximab is a humanized antibody against tumor necrosis factor alpha TNF-alpha) that is used in the treatment,of Crohn's disease and rheumatoid arthritis.

Dahlen R, et al. Infliximab inhibits activation and effector functions of peripheral blood T cells in vitro from patients with clinically active ulcerative colitis.Scand J Immunol. 2013 Sep;78(3):275-84.
Dahlen R, et al. Infliximab inhibits activation and effector functions of peripheral blood T cells in vitro from patients with clinically active ulcerative colitis.Scand J Immunol. 2013 Sep;78(3):275-84.
B. M. Assas, et al. Anti-inflammatory effects of infliximab in mice are independent of tumour necrosis factor alpha neutralization.Clin Exp Immunol. 2017 Feb; 187(2): 225-233.

Small volumes of Infliximab, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5759566 is an inhibitor targeting Infliximab.