DiR Inhibitor – Iodide [1,1'-Dioctadecyl-3,3,3',3'-Tetramethylindotricarbocyanine Iodide]

DiI, DiO, DiD and DiR Dyes are a family of lipolyphilic fluorescent dyes used to label cell membranes and hydrophobic tissues. These are environmentally sensitive fluorescent dyes that increase their fluorescence intensity significantly when they bind to membranes or to liposophile biomolecules such as proteins, although their fluorescence intensity is weak in water. They have high quenching coefficient, polarization dependence and short excitation life.Once applied to cells, the dye gradually diffuses through the cell's plasma membrane, leading to staining of the entire cell at its optimum concentration. Their different fluorescent colors, DiI (orange fluorescence), DiO (green fluorescence), DiD (red fluorescence), and DiR (dark red fluorescence), provide a convenient tool for multicolor fluorescence imaging analysis and flow cytometry in living cells.

Small volumes of DiR, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5759667 is an inhibitor targeting DiR. Also known as DiR iodide [1,1'-dioctadecyl-3,3,3',3'-tetramethylindotricarbocyanine iodide].